By Hilliard F. Seigler (auth.), H. F. Seigler (eds.)
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Advances in managed medical Inhalation reviews represents medical paintings offered on the third overseas Inhalation Symposium held 1991 in Hannover, FRG. The symposium coated the hot advancements during this box of study. the most toxins of curiosity have been acid aerosols, fog, and indoor toxins, whereas with reference to organic results, an emphasis used to be put on immunotoxicological and biochemical parameters.
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44 Table 1 continued. Author Reference Patient age Baruah Shanik Tallerman 49 50 37 70 51 63 56 Kherzi 17 72 42 * Presenting symptoms Site glans ulcer glans, prepuce swollen, tender penis pain, swelling glans & corpora phimosis, difficulty voiding prepuce swelling, change in color glans prepuce lesion Nodes + + + ? + + History previous melanoma of knee-probably secondary penile melanoma. disease . Eight other patients are reported alive at two years [5, 9-15], of whom five eventually succumbed to their disease [5, 9, 10, 12, 14].
The diagnosis of secondary bladder melanoma is made cytoscopically and usually presents as blue-black patches or nodules found in any portion of the bladder. The lesions may be single or multiple. No case of secondary bladder melanoma has been a single isolated lesion, but rather is only a sign of widespread disease. Attempts at curative surgery have uniformly resulted in failure . Most authors recommend transurethral resection for diagnosis and localized therapy [51, 53,111,119,123,124]. Recent reports of intra1esional BCG injection have shown some early success [125, 126].
J Pathol Bacteriol 84:307-311, 1962. 69. Best PV: A medulloblastoma-like tumour with melanin formation. J Pathol 110: 109-111, 1973. 70. Sung JH, Mastri AR and Segal EL: Melanotic medulloblastoma of the cerebellum. J Neuropathol Exp Neurol 32:437-445, 1973. 71. McCloskey JJ, Parker JC, Brooks WH and Blacker HM: Melanin as a component of cerebral gliomas: the melanotic cerebral ependymoma. Cancer 37:2373-2379, 1976. 72. Hahn JF, Sperber EE, Netsky MG: Melanotic neuroectodermal tumours of brain and skull.